nix allows for flakes which are 100% reproducible (ie. you copy paste a flake it would do the intended stuff only) , this make me realize that now we can have flakes for games like do you want inscryption , sure add this flake and this would install all dependencies and lutris etc. and you just have to link us to the gog-games.to / fitgirl-repack / dodi-repack variant (preferrably , gog-games.to since you can verify it with gog) (i have picked only the goat of gaming piracy from megathread) , imo this can give huge boost to gaming in linux and wine is literally really close to giving native performance and you wont even see the difference
the same logic can be applied to ms excel , powerpoint etc. but i dont see the point after using libreoffice (literally the best thing ever)
I think Flatpak or AppImages would be a more appropriate distribution method, as much as I love nix and flakes.